The Crystal16 is a parallel crystallization platform that allows for fast screening of crystallization parameters in 16 parallel reactors with a volume of 1.5 ml. The Crystal16 can be used for application of heating and cooling, for instance during polymorph or salt screening, but also for the determination of solubility as a function of temperature in e.g. process development and optimization. After more than 5 years of success in more than 200 companies, it is, by far, the world's most used equipment for solubility curves measurement and phase diagrams. New features in the Crystal16 include: eliminate the need for a chilled water supply, improved temperature range going from -15 °C up to 150 °C, overhead stirring, and a new software based on our successful software for the Crystalline.